Role for migratory wild birds in the global spread of avian influenza H5N8

Science
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Abstract

Avian influenza viruses affect both poultry production and public health. A subtype H5N8 (clade 2.3.4.4) virus, following an outbreak in poultry in South Korea in January 2014, rapidly spread worldwide in 2014–2015. Our analysis of H5N8 viral sequences, epidemiological investigations, waterfowl migration, and poultry trade showed that long-distance migratory birds can play a major role in the global spread of avian influenza viruses. Further, we found that the hemagglutinin of clade 2.3.4.4 virus was remarkably promiscuous, creating reassortants with multiple neuraminidase subtypes. Improving our understanding of the circumpolar circulation of avian influenza viruses in migratory waterfowl will help to provide early warning of threats from avian influenza to poultry, and potentially human, health.

Additional publication details

Publication type Article
Publication Subtype Journal Article
Title Role for migratory wild birds in the global spread of avian influenza H5N8
Series title Science
DOI 10.1126/science.aaf8852
Volume 354
Issue 6309
Year Published 2016
Language English
Publisher Science
Contributing office(s) National Wildlife Health Center
Description 5 p.
First page 213
Last page 217