CWDPRNP: A tool for cervid prion sequence analysis in program R

Bioinformatics
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Abstract

Chronic wasting disease is a fatal, neurological disease caused by an infectious prion protein, which affects economically and ecologically important members of the family Cervidae. Single nucleotide polymorphisms within the prion protein gene have been linked to differential susceptibility to the disease in many species. Wildlife managers are seeking to determine the frequencies of disease-associated alleles and genotypes and delineate spatial genetic patterns. The CWDPRNP package, implemented in program R, provides a unified framework for analyzing prion protein gene variability and spatial structure.

Additional publication details

Publication type Article
Publication Subtype Journal Article
Title CWDPRNP: A tool for cervid prion sequence analysis in program R
Series title Bioinformatics
DOI 10.1093/bioinformatics/btx333
Volume 33
Issue 19
Year Published 2017
Language English
Publisher Oxford Academic
Contributing office(s) Coop Res Unit Leetown
Description 2 p.
First page 3096
Last page 3097