CWDPRNP: A tool for cervid prion sequence analysis in program R
Bioinformatics
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Abstract
Chronic wasting disease is a fatal, neurological disease caused by an infectious prion protein, which affects economically and ecologically important members of the family Cervidae. Single nucleotide polymorphisms within the prion protein gene have been linked to differential susceptibility to the disease in many species. Wildlife managers are seeking to determine the frequencies of disease-associated alleles and genotypes and delineate spatial genetic patterns. The CWDPRNP package, implemented in program R, provides a unified framework for analyzing prion protein gene variability and spatial structure.
| Publication type | Article |
|---|---|
| Publication Subtype | Journal Article |
| Title | CWDPRNP: A tool for cervid prion sequence analysis in program R |
| Series title | Bioinformatics |
| DOI | 10.1093/bioinformatics/btx333 |
| Volume | 33 |
| Issue | 19 |
| Year Published | 2017 |
| Language | English |
| Publisher | Oxford Academic |
| Contributing office(s) | Coop Res Unit Leetown |
| Description | 2 p. |
| First page | 3096 |
| Last page | 3097 |
| Google Analytic Metrics | Metrics page |