Shortly before the beginning of the winter rainy season, one of the largest fires in California history (Thomas Fire) substantially increased the susceptibility of steep slopes in Santa Barbara and Ventura Counties to debris flows. On January 9, 2018, before the fire was fully contained, an intense burst of rain fell on the portion of the burn area above Montecito, CA. The rainfall and associated runoff triggered a series of debris flows that mobilized approximately 680,000 m3 of sediment (including boulders >4 m) at velocities up to 4 m/s down urbanized alluvial fans. The resulting destruction (including 23 fatalities, at least 167 injuries, and 408 damaged homes) underscores the need for improved understanding of debris-flow runout in the built environment, and the need for a comprehensive framework to assess the potential loss from debris flows following wildfire. We present observations of the inundation, debris-flow dynamics, and damage from the event. The data include field measurements of flow depth and deposit characteristics made 12 days after the event (before ephemeral features of the deposits were lost to recovery operations); an inventory of building damage; estimates of flow velocity; information on flow timing; soil-hydrologic properties; and post-event imagery and lidar. Together, these data provide rare spatial and dynamic constraints for testing debris-flow runout models, which are needed for advancing post-fire debris-flow hazard assessments. Our analysis also outlines a framework for translating the results of these models into estimates of economic loss based on an adaptation of the Federal Emergency Management Agency’s Hazus model for tsunamis.