Prescribed fire in dry coniferous forests of the western U.S. is used to reduce fire hazards. How large, old trees respond to these treatments is an important management consideration. Growth is a key indicator of residual tree condition, which can be predictive of mortality and response to future disturbance. Using a combination of long-term plot records and dendrochronological samples, we analyzed the effects of prescribed fire treatments from the early 1990 s on forest structure and individual tree growth in mixed-conifer forests of Lassen Volcanic National Park in northern California. Prescribed fire reduced stand live tree basal area and stem density at our sites up to 10 years following fire. Within two prescribed fire burn units and two adjacent unburned stands, we analyzed tree cores from 136 large (mean stem diameter > 70 cm) yellow pine (Pinus jeffreyi and P. ponderosa) and 136 large (mean stem diameter > 50 cm) white fir (Abies concolor). After accounting for annual precipitation, basal area increment for individual trees initially declined up to < 3 years post-fire for white fir and > 10 years post-fire for yellow pine, presumably in response to tree injuries. Growth improved for both species at a site that was burned twice, particularly for white fir. Recent average basal area increment was positively related to crown ratio and negatively associated with an index of local competition. Our findings suggest that forest management, such as prescribed fire and mechanical thinning, may be beneficial in terms of maintaining or improving tree growth among large residual trees. However, managers may want to balance the benefits of these treatments against inadvertent injury and mortality of large trees.