The U.S. Geological Survey (USGS) and the Massachusetts Office of Coastal Zone Management (CZM) have cooperated to map approximately 480 km2 of the inner continental shelf in northern Cape Cod Bay, MA. This report contains geophysical and sampling data collected by the USGS during five research cruises between 2006 and 2008. The geophysical data include (1) swath bathymetry from interferometric sonar, (2) acoustic backscatter from interferometric and sidescan sonars, and (3) subsurface stratigraphy and structure from seismic-reflection profilers. The seafloor sampling data include sediment samples, photographs, and video tracklines. These spatial data support research on the influence that sea-level change and sediment supply have on coastal evolution and help identify the type, distribution, and quality of subtidal marine habitats within the coastal zone of Massachusetts.