The U.S. Geological Survey (USGS) recently assessed the potential for undiscovered oil and gas resources of the West Greenland-East Canada Province as part of the USGS Circum-Arctic Resource Appraisal program. The province lies in the offshore area between western Greenland and eastern Canada and includes Baffin Bay, Davis Strait, Lancaster Sound, and Nares Strait west of and including part of Kane Basin. A series of major tectonic events led to the formation of several distinct structural domains that are the geologic basis for defining five assessment units (AU) in the province, all of which are within the Mesozoic-Cenozoic Composite Total Petroleum System (TPS). Potential petroleum source rocks within the TPS include strata of Ordovician, Early and Late Cretaceous, and Paleogene ages. The five AUs defined for this study-the Eurekan Structures AU, Northwest Greenland Rifted Margin AU, Northeast Canada Rifted Margin AU, Baffin Bay Basin AU, and the Greater Ungava Fault Zone AU-encompass the entire province and were assessed for undiscovered, technically recoverable resources.