The Fort Collins Science Center (FORT) is a multi-disciplinary research and development center of the U.S. Geological Survey located in Fort Collins, Colorado. FORT research focuses on the needs of land- and water-management bureaus within the U.S. Department of the Interior, other Federal agencies, and State, Tribal, and non-government organizations. We emphasize a multi-disciplinary science approach to provide information for natural resource management decisionmaking. Our vision is to maintain and continuously improve the integrated, collaborative, world-class research needed to inform effective, science-based land management. The 2011 science accomplishments report provides an executive summary highlighting key achievements, an appendix of 68 one-page accomplishment descriptions organized by U.S. Geological Survey Mission Area, and a complete list of publications and other products generated in FY2011. The executive summary includes a table cross-referencing all major FY11 accomplishments with the various Mission Areas each supports.