Water-quality changes in the Red River alluvial aquifer within the area affected by pool 1 near Vick, Louisiana, were monitored during pre-construction (1974-78) and post-construction (1984-92) of Lock and Dam 1. Changes greater or less than background values have occurred in an area within 2 miles of Lock and Dam 1, and in one well located about 10 miles west of Lock and Dam 1. Comparison between the pre-construction and post-construction water-quality analyses indicated the total hardness as calcium carbonate and concentrations of dissolved chloride, iron, and manganese generally have decreased in the Red River alluvial aquifer south of the Red River and near Lock and Dam l. The maximum decrease of the median total hardness as calcium carbonate was from 730 to 330 mg/L (milligrams per liter), dissolved chloride from 77 to 46 mg/L, dissolved iron from 18 to 6.9 mg/L, and dissolved manganese from 1.4 to 0.56 mg/L. Analyses of water from wells west of Lock and Dam 1 indicated an increase of the median total hardness as calcium carbonate was from 200 to 260 mg/L, and dissolved iron concentration was from 0.33 to 1.4 mg/L. North of the river and 1 mile west of Lock and Dam l, the median concentration of dissolved chloride increased from 45 to 130 mg/L in water from one well, and median total hardness as calcium cabonate and concentrations of dissolved iron and manganese also increased. Because well Ct-74 is completed in a sand that is in contact with a saltwater sand of Tertiary age, this increase is probably a temporal increase due to upconing after lowering the water level in the alluvial aquifer by pumping of dewatering wells during construction of Lock and Dam 1.