Surface- and ground-water data were collected and analyzed to describe the water resources of that part of Teton County, Wyoming located south of Yellowstone National Park. Wells and springs inventoried in the Teton County study area most commonly were completed in or issued from Quaternary unconsolidated deposits and Tertiary, Mesozoic, and Paleozoic rocks. The largest measured, reported, or estimated discharges were from Quaternary uncon- solidated deposits (3,000 gallons per minute), the Bacon Ridge Sandstone of Cretaceous age (800 gallons per minute), and the Madison Limestone of Mississippian age (800 gallons per minute). Dissolved-solids concentrations in water samples from Quaternary unconsolidated deposits and Tertiary, Mesozoic, and Paleozoic rocks ranged from 80 to 1,060 milligrams per liter. A time-domain electromagnetic survey of Jackson Hole indicated that the depth of Quaternary unconsolidated deposits ranged from about 380 feet in the northern part of Antelope Flats to about 2,400 feet near the Potholes area in Grand Teton National Park. A streamflow gain-and-loss study indicated that the ground-water discharge to the Snake River between gaging stations near Moran and south of the Flat Creek confluence, near Jackson, was 395 cubic feet per second. Water level contours generated from 137 water-level measurements and 118 stream altitudes indicated that water in Quaternary unconsolidated deposits flows southwest in the general direction of the Snake River.