Toxicity and oxidative stress of different forms of organic selenium and dietary protein in mallard ducklings
Links
- More information: Publisher Index Page (via DOI)
- Download citation as: RIS | Dublin Core
Abstract
Concentrations of over 100 ppm (mg/kg) selenium (Se) have been found in aquatic plants and insects associated with irrigation drainwater and toxicity to fish and wildlife. Composition of diet for wild ducklings can vary in selenium-contaminated environments. Earlier studies have compared toxicities and oxidative stress of Se as selenite to those of seleno-DL-methionine (DL) in mallards (Anas platyrhynchos). This study compares DL, seleno-L-methionine (L), selenized yeast (Y) and selenized wheat (W). Day-old mallard ducklings received an untreated diet (controls) containing 75% wheat (22% protein) or the same diet containing 15 or 30 ppm Se in the above forms except for 30 ppm Se as W. After 2 weeks, blood and liver samples were collected for biochemical assays and Se analysis. All forms of selenium caused significant increases in plasma and hepatic glutathione peroxidase activities. Se as L at 30 ppm in the diet was the most toxic form, resulting in high mortality (64%) and impaired growth (>50%) in survivors and the greatest increase in ratio of oxidized to reduced hepatic glutathione (GSH). Se as both L and DL decreased the concentrations of hepatic GSH and total thiols. Se as Y accumulated the least in liver (approximately 50% of other forms) and had less effect on GSH and total thiols. In a second experiment, in which the basal diet was a commercial duck feed (22% protein), survival was not affected by 30 ppm Se as DL, L, or Y and oxidative effects on GSH metabolism were less pronounced than with the wheat diet.
Publication type | Article |
---|---|
Publication Subtype | Journal Article |
Title | Toxicity and oxidative stress of different forms of organic selenium and dietary protein in mallard ducklings |
Series title | Archives of Environmental Contamination and Toxicology |
DOI | 10.1007/BF00203916 |
Volume | 31 |
Issue | 1 |
Year Published | 1996 |
Language | English |
Publisher | Springer |
Contributing office(s) | Patuxent Wildlife Research Center |
Description | 8 p. |
First page | 120 |
Last page | 127 |
Google Analytic Metrics | Metrics page |