| Abstract: | There is increasing documentation of allergic contact dermatitis and other effects from gold jewelry, gold dental restorations, and gold implants. These effects were especially pronounced among females wearing body-piercing gold objects. One estimate of the prevalence of gold allergy worldwide is 13%, as judged by patch tests with monovalent organogold salts. Eczema of the head and neck was the most common response of individuals hypersensitive to gold, and sensitivity can last for at least several years. Ingestion of beverages containing flake gold can result in allergic-type reactions similar to those seen in gold-allergic individuals exposed to gold through dermal contact and other routes. Studies with small laboratory mammals and injected doses of colloidal gold showed increased body temperatures, accumulations in reticular cells, and dose enhancement in tumor therapy; gold implants were associated with tissue injuries. It is proposed that Au? toxicity to mammals is associated, in part, with formation of the more reactive Au+ and Au3+ species. |
| Genre: | Article |
| ProdID: | 5224015 |
| Citation Author: | Eisler, R. |
| Citation Contributing Office: | Patuxent Wildlife Research Center |
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| Citation End Page: | 18 |
| Citation Issue: | 1 |
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| Citation Language: | English |
| Citation Larger Work Title: | Biological Trace Element Research |
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| Citation Number Of Pages: | 18 |
| Citation Online Only Flag: | |
| Citation Phsyical Description: | 1-18 |
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| Citation Public Comments: | 6164_Eisler.pdf |
| Citation Publisher: | U.S. Fish and Wildlife Service |
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| Citation Search Results Text: | Mammalian sensitivity to elemental gold (Au?); 2004; Article; Journal; Biological Trace Element Research; Eisler, R. |
| Citation Start Page: | 1 |
| Citation Volume: | 100 |
| Citation Year: | 2004 |
| Type: | citation/reference |
| Text: | Mammalian sensitivity to elemental gold (Au?); 2004; Article; Journal; Biological Trace Element Research; Eisler, R. |
| URL (THUMBNAIL): | http://pubs.er.usgs.gov/thumbnails/outside_thumb.jpg |
| URL (DOCUMENT): | http://dx.doi.org/10.1385/BTER:100:1:001 |
| Date Other: | Wed, 16 Jun 2010 12:18 -0500 |
| Publisher: | U.S. Fish and Wildlife Service |
