The tectonic and sedimentary environment of the Central North American Rift System (CNARS) provides an excellent setting for major mineral deposits. Major north-northeast-trending high-angle normal or reverse faults and northwest-trending transcurrent fault systems may exercise control over ore forming processes. Gabbro and basalt are the dominant igneous rock types. Carbonatite and kimberlite occur in Nebraska and Kansas. Concentrations of Cu, Ni, Co, Ti, Au, Ag and PG minerals are known to occur in this setting. Arkosic sandstone, siltstone, shale, and minor carbonate units occur on top of the rift basalts and in flanking basins where they may reach thicknesses of 10 km (6 miles). The potential for stratiform or unconformity-related metalliferous deposits should be considered. The rift as a whole remains largely unexplored.