Geographic variation in marine turtle fibropapillomatosis

Journal of Zoo and Wildlife Medicine
By: , and 



We document three examples of fibropapillomatosis by histology, quantitative polymerase chain reaction (qPCR), and sequence analysis from three different geographic areas. Tumors compatible in morphology with fibropapillomatosis were seen in green turtles from Puerto Rico and San Diego (California) and in a hybrid loggerhead/ hawksbill turtle from Florida Bay (Florida). Tumors were confirmed as fibropapillomas on histology, although severity of disease varied between cases. Polymerase chain reaction (PCR) analyses revealed infection with the fibropapilloma-associated turtle herpesvirus (FPTHV) in all cases, albeit at highly variable copy numbers per cell. Alignment of a portion of the polymerase gene from each fibropapilloma-associated turtle herpesvirus isolate demonstrated geographic variation in sequence. These cases illustrate geographic variation in both the pathology and the virology of fibropapillomatosis.

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Additional publication details

Publication type Article
Publication Subtype Journal Article
Title Geographic variation in marine turtle fibropapillomatosis
Series title Journal of Zoo and Wildlife Medicine
DOI 10.1638/04-051.1
Volume 36
Issue 3
Year Published 2005
Language English
Publisher American Association of Zoo Veterinarians
Contributing office(s) National Wildlife Health Center
Description 4 p.
First page 527
Last page 530
Online Only (Y/N) N
Additional Online Files (Y/N) N