Isolation and identification of trichothecenes from Fusarium compactum suspected in the aetiology of a major intoxication of sandhill cranes

Journal of Agricultural and Food Chemistry
By: , and 

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Abstract

Isoneosolaniol (4,8-diacetoxy-12,13-epoxytrichothec-9-ene-3,15-diol) and other unidentified trichothecene mycotoxins were isolated from culture extracts of two highly toxigenic strains of Fusarium compactum cultured from waste peanuts involved in an acute intoxication of sandhill cranes (Grus canadensis). Neosolaniol and other unidentified trichothecenes were detected in waste peanuts collected from affected areas. The structure of isoneosolaniol was determined by 1H and 13C NMR analyses and by high-resolution mass spectometry. Isoneosolaniol was hightly toxic to 1-day-old chickens and to a HEp2 cell culture assay. It was concluded that the most logical cause of the sandhill crane intoxication was Fusarium spp. Contaminated peanuts and various trichothecene mycotoxins acting alone or in conjunction with other Fusarium mycotoxins.

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Additional publication details

Publication type Article
Publication Subtype Journal Article
Title Isolation and identification of trichothecenes from Fusarium compactum suspected in the aetiology of a major intoxication of sandhill cranes
Series title Journal of Agricultural and Food Chemistry
DOI 10.1021/jf00084a009
Volume 36
Issue 6
Year Published 1988
Language English
Publisher ACS Publications
Contributing office(s) National Wildlife Health Center
Description 5 p.
First page 1163
Last page 1167
Country United States
State Texas
County Gaines County
Other Geospatial Cedar Lake
Online Only (Y/N) N
Additional Online Files (Y/N) N
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