Near-surface site factors and the effects of deep structural focusing were estimated in the Santa Monica Mountains and Santa Monica, California, from a portable array of 75 seismic stations deployed during the Los Angeles Region Seismic Experiment, Phase II (LARSE II). The objective was to examine further the origin of seismic wave amplification in the region of intense damage south of the Santa Monica Fault from the Northridge earthquake. The analysis used normalized spectral amplitudes in the 4- to 8- and 8- to 12-Hz range in direct and coda waves from local earthquakes in Santa Paula, Northridge, Redlands, and Hector Mine. Coda waves indicated that site factor amplifications are larger south of the Santa Monica fault relative to the north. Spectral ratios of direct S waves, corrected for site effects, show additional amplificaton south of, and adjacent to, the Santa Monica fault, attributable to focusing by a deeper structure. Gao et al. (1996) concluded that localized focusing effects contributed to anomalous P- and S-wave amplification in the Santa Monica damage zone for Northridge aftershocks within a specified range of azimuths. In an attempt to reproduce the hypothesized focusing from the Northridge earthquake, two shots (4000 and 3750 lb.) were detonated, one at Pyramid Lake, a distance of about 69 km to the north-northwest of central Santa Monica, and the other near Fort Tejon, a distance of 91 km. The azimuth of the shots was chosen to be that expected to give anomalous amplification. At these distance steeply incident seismic energy from Pg/PmP waves are expected to pass through the underground focusing structure and be selectively amplified. After the local site factors are removed, the waveforms from the Fort Tejon shot exhibited localized amplification adjacent to and south of the fault, 2-3 times larger than that of the surrounding area. The effect is less for waves from the Pyramid Lake shot, which could be due to their higher angle of incidence. The observations lend support to the argument that deep structural focusing is an important factor in determining azimuth-dependent amplification of seismic waves along a basin edge.