Phylogenetic and pathogenic characterization of novel adenoviruses from long-tailed ducks (Clangula hyemalis)

Virology
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Abstract

Novel adenoviruses were isolated from a long-tailed duck (Clangula hyemalis) mortality event near Prudhoe Bay, Alaska in 2000. The long-tailed duck adenovirus genome was approximately 27 kb. A 907 bp hexon gene segment was used to design primers specific for the long-tailed duck adenovirus. Nineteen isolates were phylogenetically characterized based on portions of their hexon gene and 12 were most closely related to Goose adenovirus A. The remaining 7 shared no hexon sequences with any known adenoviruses. Experimental infections of mallards with a long-tailed duck reference adenovirus caused mild lymphoid infiltration of the intestine and paint brush hemorrhages of the mucosa and dilation of the intestine. This study shows novel adenoviruses from long-tailed ducks are diverse and provides further evidence that they should be considered in cases of morbidity and mortality in sea ducks. Conserved and specific primers have been developed that will help screen sea ducks for adenoviral infections.

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Additional publication details

Publication type Article
Publication Subtype Journal Article
Title Phylogenetic and pathogenic characterization of novel adenoviruses from long-tailed ducks (Clangula hyemalis)
Series title Virology
DOI 10.1016/j.virol.2015.07.026
Volume 485
Year Published 2015
Language English
Publisher Elsevier
Publisher location Amsterdam, Netherlands
Contributing office(s) National Wildlife Health Center, Contaminant Biology Program
Description 9 p.
First page 393
Last page 401
Country United States
State Alaska
Other Geospatial Beaufort Sea, Prudhoe Bay, Simpson Lagoon
Online Only (Y/N) N
Additional Online Files (Y/N) N
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