Successful water-resource management requires thorough knowledge and understanding of the relations among water-quality contaminate sources and the factors that affect the transport throughout a hydrologic system. Surface-water modeling is a valuable tool that can be applied to help advance and achieve the understanding of these dynamic relations. Spatially Referenced Regressions on Watershed Attributes (SPARROW) is one such model that uses nonlinear statistical methods to define conceptual and spatial relations among quantities of contaminant sources, monitored contaminant load, aquatic transport processes. NHDPlus Version 2 (V2) is a digital representation of a hydrologic network of streams and associated catchments. The dataset provides the fundamental spatial framework for SPARROW modeling.