The goal of this project was to facilitate climate change adaptation that contributes to social-ecological resilience, ecosystem and species conservation, and sustainable human communities in southwestern Colorado. The team developed and piloted integrated adaptation planning tools and principles that merge the strengths of the iterative scenario process, the Adaptation for Conservation Targets (ACT) planning framework, institutional analysis, and climate modeling. These tools and principles generated practical strategies and scientific knowledge to advance climate change adaptation in both the Gunnison River Basin and San Juan River Basin and, potentially, other landscapes. A key objective of this project was to work with decision-makers to develop social-ecological adaptation strategies and coordinate actions to reduce the impacts of a changing climate on nature and people. To accomplish this, the project blended science (biophysical and social) and participatory approaches to integrate expert knowledge, land management decision making, and local needs. These adaptation strategies and their creation process were documented by the project team to assist communities and scientists elsewhere who are grappling with the challenges posed by climate change.