This report describes the water-resources activities of the U.S. Geological Survey (USGS), Wyoming District. The activities are classified as data- collection programs and water-resources-appraisal projects. Much of the work is done in cooperation with other agencies. During fiscal years 1992 and 1993, cooperators included nine local agencies, two Native American tribes, seven State agencies, and nine Federal agencies. This report is a biennial progress report to the cooperating agencies and the general public. During fiscal year 1992, the Wyoming District operated 166 streamflow stations, 1 reservoir station, 93 surface-water-quality stations, 34 fluvial-sediment stations, 85 ground- water-level observation wells, and 100 ground- water-quality sites, of which 25 were sampled during fiscal year 1992. Descriptions, location maps, and status statements are given for the 4 long-term data-collection projects and for 16 water-resources appraisal projects that were active (funded) during fiscal year 1992 or 1993. Also included are lists of 14 projects that were completed between May 1991 and June 1993; and 2 projects for which funding ended prior to 1993 and that are completed except for the final report(s). The final section is a bibliographic listing of reports by USGS authors about the water resources of Wyoming.