Effects of depleted uranium on survival, growth, and metamorphosis in the african clawed frog (Xenopus laevis)
Links
- More information: Publisher Index Page (via DOI)
- Download citation as: RIS | Dublin Core
Abstract
Embryos (stage 8-47, Nieuwkoop and Faber) of the African clawed frog (Xenopus laevis) were subjected to water-borne depleted uranium (DU) concentrations that ranged from 4.8 to 77.7 mg/Lusing an acute 96-h frog embryo teratogenesis assay-Xenopus (FETAX). In a chronic 64-d assay, X. laevis (from embryo through metamorphosis; stages 8-66) were subjected to concentrations of DU that ranged from 6.2 to 54.3 mg/L Our results indicate DU is a non teratogenic metal. No effects on mortality, malformations, or growth were observed in the 96-h FETAX with concentrations of DU that ranged from 4.8 to 77.7 mg/L From stage 8 to stage 47, X. laevis tadpoles do not actively feed and the gills are not well developed. Thus, uptake of DU was reduced despite exposure to elevated concentrations. The 64-d assay resulted in no concentration response for either mortality or malformations; however, a delay in metamorphosis was observed in tadpoles subjected to elevated DU concentrations (from 13.1 to 54.3 mg/L) compared to tadpoles in both the well-water control and reference. The delay in metamorphosis was likely due to increasing body burden of DU that ranged from 0.98 to 2.82 mg/kg. Copyright?? Taylor & Francis Inc.
| Publication type | Conference Paper |
|---|---|
| Publication Subtype | Conference Paper |
| Title | Effects of depleted uranium on survival, growth, and metamorphosis in the african clawed frog (Xenopus laevis) |
| DOI | 10.1080/15287390590912595 |
| Volume | 68 |
| Issue | 11-12 |
| Year Published | 2005 |
| Language | English |
| Larger Work Title | Journal of Toxicology and Environmental Health - Part A |
| First page | 951 |
| Last page | 956 |
| Google Analytic Metrics | Metrics page |